pH-Responsive Nano-Hydrogel Carrier for Controlled Albumin Delivery
- Authors
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Fenilkumar Patel
Author
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- Keywords:
- Hydrogel, pH-Responsive, Albumin Delivery, Covalent Polymer, Controlled Release, Swelling Behavior, Targeted Drug Delivery
- Abstract
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Researchers have designed a novel hydrogel that modifies protein delivery. The polymer synthesized from phthalic anhydride and glycerol with acrylic acid crosslinking had a nano-size (~ 68 nm) and pH-sensitive swelling. The authors evaluated the conditions for improved bovine serum albumin (BSA) loading and release from the nano-hydrogel. The performance of the hydrogel was improved under alkaline conditions (pH 8.0) compared to acidic conditions (pH 2.2). The maximum loading and release performance was observed at 6 hrs. A tunable and pH-sensitive system exhibiting pH-responsive swelling and BSA release behavior for drug delivery applications. More research is required to determine how it performs under physiological conditions.
- References
- Cover Image
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- Published
- 2026-10-23
- Issue
- Vol. 1 No. 3 (2026)
- Section
- Articles
- License
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Copyright (c) 2026 International Journal of Clinical Research and Medical Sciences
This work is licensed under a Creative Commons Attribution 4.0 International License.
